Abstract
Lithium in blood serum can be determined rapidly and with sufficient accuracy by atomic absorption measurement of solutions of blood serum diluted with water, using either a conventional atomic absorption spectrophotometer or one with a resonance monochromator. Calibrating solutions contain sodium and potassium at approximately the concentrations present in the serum solutions as these metals cause a slight enhancement of lithium absorption in the air/coal gas flame. Results are reproducible to within ±0.2 μg Li/ml in the serum and the limits of sensitivity attainable for samples diluted 1:10 are 0.3μg Li/ml in the serum with the conventional instrument and 0.6 μg Li/ml in the serum with the resonance monochromator.
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