The application of polypropylene mesh for testicular prosthesis in surgical castration for patients with prostate cancer

Yao-Hui Xia,Jie An,Peng-Fei Wang,Rui Qin,Yong-Qiang Xia,Bo Kong,Wei Huang,Chun-Xiao Yu

doi:10.1186/s12957-019-1709-2

Abstract

BackgroundTo explore whether a polypropylene mesh is suitable for application as a new material for testicular prostheses.MethodsThe data of 65 patients with advanced prostate cancer who underwent surgical castration in hospital were collected and analyzed. Patients who preferred to undergo traditional orchidectomy (n = 16) were assigned to the control group, and patients who underwent subcapsular orchiectomy plus implantation of a polypropylene mesh testicular prosthesis (n = 49) were assigned to the experimental group. The presence of hematoma, infection, and other complications in patients in these two groups were investigated at 3 and 12 months following the surgery. The patients were also followed up using a self-designed testicular castration satisfaction questionnaire.ResultsA higher score indicated greater satisfaction. The mean score was 15.33 ± 2.85 in the experimental group and 4.63 ± 1.45 in the control group at 3 months after the surgery. The mean score was 14.92 ± 1.74 in the experimental group and 4.25 ± 1.61 in the control group at 12 months after the surgery. The difference between the two groups was statistically significant at the two time points (P < 0.01).ConclusionsCompared with orchidectomy alone, patients were more satisfied with subcapsular orchiectomy plus the implantation of a polypropylene mesh testicular prosthesis for the treatment of advanced prostate cancer. Furthermore, the polypropylene mesh testicular prosthesis maintained its original character over the duration of the study, with a good long-term effect. Thus, implantation of a polypropylene mesh testicular prosthesis is indicated to be safe and effective, and polypropylene mesh is potentially useful as a new material for testicular prostheses.

Highlights

Studies have revealed that the incidence of prostate cancer is becoming significantly higher in men > 60 year old [1, 2]
Since the quantification standard of the effect after orchidectomy and testicular prosthesis implantation could not be searched, and in order to evaluate the application value of the implantation of the polypropylene mesh testicular prosthesis for prostate cancer patients undergoing surgical castration, the investigator for this study developed an observation questionnaire of testicular surgery using the following three items: the sense of the testis size, the sense of testicular rigidity, and the special indisposition of the testis
This study found that when the polypropylene mesh testicular prosthesis was implanted into the albuginea in the testis, the testicular prosthesis and tissue exhibited an Scores at 3 months after operation

Summary

Introduction

Studies have revealed that the incidence of prostate cancer is becoming significantly higher in men > 60 year old [1, 2] Among these patients, some patients lose the chance of radical surgery due to serious cardiovascular disease, pulmonary dysfunction, and other diseases [3]. Some patients refuse simple endocrine therapy due to heavy economic burden and are afraid of the inferiority complex when facing orchidectomy. This segment of patients often gives up the opportunity of treatment. The histocompatibility and the satisfaction following surgical castration of the two groups of patients were compared. To explore whether a polypropylene mesh is suitable for application as a new material for testicular prostheses

Methods

Discussion

Conclusion