Abstract

High-throughput sequencing technology is a revolutionary technological innovation of sequencing technology. This technology, with low cost and high throughput data, brought new research methods and solutions for genomics and post genomics research. In plant and animal research, the high-throughput sequencing, leading a landmark innovation in scientific research model, can improve researches in the genome, transcriptome and epigenome, and multi-level system. In this review, we described the research progress of high-throughput sequencing applications in plant and animal genomics and functional genomics, and the current status and hot points of high-throughput sequencing technology. We also discussed the trends in the further application of high-throughput sequencing.

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