The application of harmonic techniques to enhance resolution in mesh-based x-ray phase imaging

Abstract

X-ray phase-contrast imaging produces significantly higher contrast than the conventional attenuation-based imaging. However, phase contrast typically requires small low-power sources or precisely machined and aligned gratings to generate the required spatial coherence. To overcome this limitation, we use a simple wire mesh to produce a periodic intensity pattern in the illumination. Distortions in this pattern upon propagation through an object can be used to produce phase contrast images. Unlike Talbot-grating-based techniques, this directly provides a measure of the phase gradient. Due to periodicity, fast Fourier transforms enable rapid retrieval of the phase contrast image. The high contrast of the mesh pattern allows a significant relaxation of the coherence requirement. However, the resolution of the phase contrast image is normally limited by the mesh period. We demonstrate that employing wider windowing functions during the Fourier processing substantially improves the spatial resolution at the cost of introducing artifacts in the reconstructed images. In order to remove these artifacts, a method is presented to combine images acquired while spatially shifting the mesh. Experimental results demonstrate the successful removal of these artifacts. This offers a method for significant resolution improvement in mesh-based phase-contrast imaging, enabling high resolution phase contrast images with a significant relaxation of source coherence requirements.