The application of dynamic blood glucose monitoring on patients with insulinoma

Abstract

Objective To explore the application value of dynamic blood glucose monitoring in the blood glucose monitoring for patients with insulinoma. Methods A total of 16 patients with insulinoma treated in our hospital from October 2013 to December 2015 were taken as the observation group.While 15 cases with hypoglycemia caused by the type 2 diabetic reaction were taken as the diabetic group and 15 cases of normal healthy volunteers as control group.Three groups all received 72 hours dynamic blood glucose monitoring.The general information, the mean value of 24 hours blood glucose, the standard deviation of the blood glucose, the maximum of the blood sugar, the minimum of the blood sugar, the maximum fluctuation range and the frequency and duration of hypoglycemia were compared. Results The BMI index and insulin releasing index of the observation group were significantly higher than that of the diabetic group and the control group (P<0.05). The HbAlc of diabetic group was significantly higher than that of the observation group and control group (t=4.615, 4.273, P<0.05), while the MAD of the diabetic group was significantly lower than that of the observation group and control group (t=5.124, 5.238, P<0.05). The 72-hour starvation-exercise test found 13 positive cases and 3 negative cases in the observation group.The average blood glucose and blood glucose of the observation group were (4.69 + 1.53) mmol/L and (2.46 + 0.29) mmol/L respectively, which were significantly lower than that of the diabetic group and the control group (P<0.05). The maximum blood glucose level and the maximum fluctuation range of the observation group were significantly lower than that of the diabetic group, which were significantly higher than that of the control group (P<0.05). The frequency of hypoglycemia of observation group was significantly higher than that of the diabetic group and the duration of hypoglycemia was significantly longer than that of the diabetic group (P<0.05). Conclusion Dynamic blood glucose monitoring can better reflect the dynamic changes of blood glucose of patients with insulinoma, which shows a strong application value. Key words: Insulinoma; Blood glucose monitoring; Dynamic blood glucose monitoring; Application value