Abstract

Objective To evaluate the safety and feasibility of combined spinal-epidural anesthesia and Combined Midazolam used for laparoscopic gynecology Operation.Methods 500 patients of ASA grade Ⅰ-Ⅱundergoing laparoscopic gynecology surgery were randomly devided into combined spinal-epidural anesthesia group(group CSEA,n=250)and general anesthesia group(group GA,n=250),The variation of peri-anesthesia mean heart rate(HR),respiration rate(RR),arterial pressure(MAP),pulse oxygen saturation(SpO2)were tested and recorded.The wake time and the post-operative(in24hour)complications were observed.Results Referring to all patients,there were not any significant differences in BP,HR,RR,SpO2(P>0.05).The wake time was significantly shorter in Group CSEA than in Group GA(P<0.01),The incidence of postoperative complication(nausea,vomiting,restlessness)was significantly lower in Group CSEA than in Group GA(P<0.05).Conclusion The combined spinal-epidural anesthesia and combined Midazolam used for laparoscopie gynecology Operation is safe and feasible,and easier and more economical general anesthesia. Key words: Combined spinal-epidural anesthesia; Midazolam,Laparoscopic gynecology Operation

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