The application of a corrected hematocrit to triiodo-L-thyronine I-131 red blood cell uptake test.

Abstract

1) The validity of using the corrected hematocrit, which was obtained on the basis of assuming that 85μ3 is the ideal corpuscular volume for red blood cells, was discussed. 2) Ninety-two patients were examined by the T3 uptake test, and comparison of the data, obtained by Hamolsky's and Adams' calculations as well as by modified ones applying the corrected hematocrit, was done. 3) The work presented here showed fundamental difference in the locations of the boundaries between the three different diagnostic categories of thyroid function introduced by Adams et al. and Hamolsky et al. 4) This report showed higher labeling of T3 by red blood cells than Hamolsky's reports. The range of K for the euthyroid group was narrower mthis work than in the Adams' report. 5) The results obtained by using the corrected hematocrit on Hamolsky's and Adams' calculations showed better separation between the three diagnostic categories. As long as the corrected hematocrit was applied on Hamolsky's and Adams' calculations, both methods were equally valid to separate the three diagnostic categories.