The Application and Challenge of Non-Human Primate Experimental Animals in the Field of Neuroscience

Abstract

Non-human primates (NHPs) are highly valued in the field of neuroscience due to their similarity to humans in terms of brain structure and function. They exhibit complex social behaviors and cognitive abilities, and their use in research has led to significant breakthroughs in the understanding of brain development, neurodegenerative diseases, and psychiatric disorders. In recent years, the breeding and use of NHPs has expanded, making them increasingly important as experimental animals. However, with this expansion comes the need for researchers to address important biosafety and animal ethics concerns. It is critical that animal welfare is ensured and that scientific objectives are achieved while observing ethical guidelines. This paper aims to provide an overview of NHPs in neuroscience, their applications in research, and the ethical considerations that must be taken into account. It highlights the various breeding and handling practices that are employed to ensure the health and welfare of NHPs in experimental settings. Additionally, the paper summarizes the challenges associated with the use of NHPs in research and the benefits that have been realized from their use. Overall, this paper underscores the importance of recognizing the role of NHPs in neuroscience, and the responsibility that researchers have to ensure their welfare and to address ethical considerations. By doing so, researchers can continue to advance our understanding of the brain and develop new treatments for neurological and psychiatric disorders.