Abstract
Using the chemiluminescence method, the effective concentration of antioxidants (AO) and their antiradical activity (ARA) have been measured for 13 plant extracts. All extracts demonstrated higher ARA than that of the synthetic antioxidant ionol. The highest ARA was found in extracts from Larix dahurica, Hypericum perforatum, Potentilla fruticosa, Aronia melanocarpa, and Rhaponticum carthamoides. Synergistic action was found for combinations of extracts from Aronia + Rhaponticum, Larix + Hibiscus, and Schizandra + Aronia; the synergistic effect β was 38, 33, and 22%, respectively. This effect may be attributed to compounds present in these extracts. Phospholipids (the phospholipid complex Lipoid S40) lacking any antioxidant effect alone, showed a potent synergistic effect in combination with the Aronia extract (β = 60%) and the Silybum extract (β = 41%). Combinations of plant extracts with the phospholipids complex potentiated their inhibitory activity by increasing the induction period. Clinical trials have demonstrated, the combinations used may be recommended as an additional component in the complex therapeutic treatment of such chronic diseases as cardiovascular and hepatobiliary and also as an individual prophylactic agent.
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