The antioxidant and antibacterial study of Canarium indicum L. latex extract

Abstract

Recently, plant extracts are natural additives that are in great demand. Many biological activities of plant extracts in the fields of food and health, make research on plant extracts quite rapid. Canarium indicum L. is one of the most famous fruits in Indonesia. However, usually only the seed of C. indicum that was studied such as anti-inflammatory, antirheumatic, and hepatoprotective. In this paper, the antimicrobial and antioxidant activities of C. indicum latex were studied. The C. indicum extract were prepared by maceration method using ethanol for 48 hours. After the evaporation, the crude extracts were evaluated its biological activity. The antibacterial activity was performed using dilution method and the antioxidant activity was using DPPH assay. The scavenging activity of C. indicum latex extracts values in the range of 10.92 – 58.36% with the extract concentration of 100 to 800 ppm, respectively. The antibacterial activity of C. indicum latex extract was conducted against Gram-positive bacteria (S. aureus) and Gram-negative bacteria (E. coli). The inhibition zone C. indicum was 6.39±0.06 mm against S. aureus and 2.38±0.62 mm against E. coli at extract concentration of 10000 ppm. The results obtained indicate that C. indicum latex extract is favourable to be applied in the fields of medicine and health.