Abstract
The aim of study was to evaluate the efficacy of antimicrobial composition of amikacin with dioxydin and polyvinylpyrrolidone as a biodegradable prolonging agent for the post-surgery infections prophylaxis. The data obtained show the efficacy of the amikacin combination with dioxydin based on high-molecular weight polyvinylpyrrolidone and an opportunity to it's application for the post-surgery infections prophylaxis in traumatology, orthopedics and other surgery areas.
Highlights
Îíêààìçûîíâîàöëèâòàîðïíûîò-ãàðõàíinóëvîitöroèòòàîðêíñûè÷ååêñëêåîòåêäèåèéñêòëâåèòåêè ýíäîòåëèÿ ñîñóäîâ [15]
The aim of study was to evaluate the efficacy of antimicrobial composition of amikacin
The data obtained show the efficacy of the amikacin combination with dioxydin based on high-molecular weight polyvinylpyrrolidone
Summary
Îíêààìçûîíâîàöëèâòàîðïíûîò-ãàðõàíinóëvîitöroèòòàîðêíñûè÷ååêñëêåîòåêäèåèéñêòëâåèòåêè ýíäîòåëèÿ ñîñóäîâ [15]. Ðåçóëüòàòû èçó÷åíèÿ äåéñòâèÿ ëå÷åáíîé êîìïîçèöèè íà ìîäåëè ýêñïåðèìåíòàëüíîãî îñòåîìèåëèòà ó êðîëèêîâ ïîêàçàëè, ÷òî íà 3 ñóòêè ïîñëå îïåðàöèè ó æèâîòíûõ îáåèõ ãðóïï áûëè âûðàæåíû êëèíè÷åñêèå ñèìïòîìû âîñïàëåíèÿ Íà 7 ñóòêè ó æèâîòíûõ ïîäîïûòíîé ãðóïïû, â îòëè÷èå îò êîíòðîëüíîé, íàáëþäàëè áîëåå èíòåíñèâíóþ äèíàìèêó óìåíüøåíèÿ îòåêà è èíôèëüòðàöèè òêàíåé.
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