Abstract
THE activity of brain tissue extract in the mechanism of blood coagulation is considered to be equivalent to a combination of platelets, antihaemophilic globulin and Christmas factor1 (plasma thromboplastin component). The latter two blood-clotting factors have been separated in different ethanol fractions of plasma. It was thus of interest, following our report on the isolation of antihaemophilic globulin from brain tissue2, to study the antihaemophilic and Christmas factor activities of various ethanol fractions obtained from brain extract.
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