THE ANTIDEPRESSANT USAGE RATE AND TREATMENT OUTCOMES FOR OUTPATIENTS WITH DEPRESSION AT CAN THO PSYCHIATRIC HOSPITAL FROM 2022 TO 2023

Abstract

Background: Depression is a prevalent condition that affects individuals globally. It can cause significant emotional pain and hinder one's ability to perform well in various settings such as work, school, and home. Diagnosing and treating depression can be challenging due to limited resources, a shortage of trained healthcare providers, and the social stigma often attached to mental disorders. Objectives: The objective of this study is to identify the types and quantities of antidepressant drugs prescribed and received, as well as to assess the outcomes of treatment for depressed patients who received outpatient care at Can Tho Psychiatric Hospital between 2022 and 2023. Materials and methods: A descriptive cross-sectional study of 255 patients aged 18 and older was conducted at Can Tho Psychiatric Hospital in 2022-2023. Data were analyzed using SPSS 20. Results: Most patients (39.6%) were aged 18-29, and 76.1% were female. Patients had varying levels of depression, with the majority having moderate to severe depression. The most commonly prescribed first-line antidepressants were fluoxetine (35.3%) and sertraline (50.6%), both of which are SSRIs (Selective serotonin reuptake inhibitors). After 2 and 6 weeks of treatment, patients' depression levels significantly improved (p<0.001). Remission rates increased from 29.3% (±12.4%) after 2 weeks to 69.9% (±17.8%) after 6 weeks of treatment, with a statistically significant difference (p<0.001). While only the sleep disorder symptom group showed improvement after 2 weeks, all symptoms showed a high remission rate after 6 weeks of treatment. Improvement rates after 2 and 6 weeks were 8.6% and 85.9%, respectively. Conclusions: SSRIs are commonly prescribed as the first-line treatment for outpatients experiencing depression. Sertraline is the most frequently prescribed medication. Depression is prevalent in young women between 18 and 29, many of whom experience severe symptoms. Treatment can greatly improve all symptoms in six weeks, with sleep disturbances showing the most improvement. It is important to seek help promptly and recognize symptoms to achieve the best result.