Abstract
In recent years, various marine derived products have been becoming prevalent and popular in the beauty from within market due to solid scientific research that proved their potential to improve the skin conditions and reverse facial aging. In our study, a proprietary and patented combination consisting of 5 marine peptides was investigated regarding its benefits against facial antiaging. The human dermal fibroblast tests indicated mRNA expressions of AQP3, and type III collagen were significantly enhanced by the composition compared to each individual ingredient. The pilot-scale study in which 10 individuals orally supplemented with the composition for 28 days had increased contents of both type I and type III collagens while the ratio of type I to type III collagens decreased to a level comparable to that of young adolescents. This should be the first research demonstrating the efficacies of marine peptides combination on facial skin improvement from the perspective of its ability to reverse the ratio of type I to type III collagen, which definitely provided a valuable target for the futuristic intervention.
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