The Antagonistic and Synergistic Comparison of the Antimicrobial Characteristics of Extracts of Some Herbs

Abstract

In the present study, the antagonistic and synergistic effects of Achillea millefolium L., Anthemis cretica L., Cichorium intybus L., Euphorbia seguieriana Necker and Hypericum perforatum L plant extracts collected from Samsun were investigated. Gram negative bacteria; Escherichia coli, Acinetobacter baumannii, Salmonella typhimurium, Gram positive bacteria; Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes were used as research materials. In the research, methanol and diethyl were used as solvents. The antibacterial activities of the extracts were determined by microbroth dilution method. According to the results of the research; all plant extracts obtained using both methanol and diethyl ether solvent were determined to be more effective against gram positive bacteria. While the whole plant extract showed the most effect on Bacillus cereus bacteria, Hypericum perforatum L. methanol extract was the most effective plant against gram positive bacteria. Achillea millefolium L.: Cichorium intybus L., Achillea millefolium L.: Hypericum perforatum L. and Cichorium intybus L.: Hypericum perforatum L. methanol mixture extracts and Achillea millefolium L.: Hypericum perfarotum L. diethyl ether extract showed a synergistic effect, while other plant mixture extracts showed semi-synergistic or ineffective properties.