THE ANALYTICAL STUDY OF “ROLE OF VARIOUS ETIOLOGICAL FACTORS FOR THE PRECIPITATION OF ACUTE SEIZURES

Abstract

Background: Seizures are a result of shift in the normal balance of excitation and inhibition within the central nervous system. Acute symptomatic seizures are those caused or provoked by acute medical or neurological illness Aims And Objectives: 1.To study the etiological spectrum of acute symptomatic seizures. 2. To evaluate new onset seizures by clinical and appropriate laboratory and radiological evaluation Methods: 170 patients attending the outpatient department and emergency department with diagnosis of acute seizures in Department of Medicine and allied specialties in KIMS &RF hospital from SEPTEMBER 2020 to OCTOBER 2022 are selected for the study Results: In this study ASS was seen more in males (60%) than females (40%).GTCS was seen in 75.2% subjects, 21.1% subjects presented with focal seizures and 3.52% subjects had focal seizures with secondary generalisation. Metabolic insults were found in 25.9% subjects ,Vascular insults 15.9% , Drug withdrawal seizures 15.9%, adult onset seizures 5%, Primary generalized epilepsy 8.8%, Cerebral Venous Sinus thrombosis 7.6%, Alcohol withdrawal in 4.1%,trauma 5.3%, neurocysticercosis 2.4%,tuberculoma 2.9%,drug poisoning 1.2% Conclusion: Incidence of ASS was more during early adulthood and middle aged persons. Metabolic insults accounted for a large portion (25.9%) ,vascular insults (15.9%), drug withdrawal seizures(15.9%), seizures secondary to CVT (7.6%), trauma(5.3%), alcohol withdrawal(4.1%), NCC (2.4%), tuberculoma (2.9%).Acute symptomatic seizures continue to be a useful concept for classication and prognosis