The analysis to risk factors of affecting the long-term patency ratio of stent planted in arteriosclerosis subclavian artery

Abstract

The discussion of risk factors of affecting the long-term patency ratio of stent planted in arteriosclerosis subclavian artery. To analyse the correlation between preprocedural white blood cell count, antiplatelet agents therapy, residual stenosis in the stent, the preprocedural lesion degree of subclavian artery, serum lipid, blood sugar, blood press et al, and long-term patency of stent by Logistic regression. To explore the significant difference in preprocedural white blood cell count (WBC), antiplatelet agents therapy, residual stenosis, the preprocedural lesion degree of subclavian artery, serum lipid, blood sugar, blood press and so on between non-patency group (15 patients) and patency group (139 patients). To compare the significant difference of patency ratio of stent at the end of the survey between higher WBC (> 7.08 × 10⁹/L) group (45 patients) and lower WBC (≤ 7.08 × 10⁹/L) group (109 patients) by χ²-test. Among 154 stents planted in subclavian artery, the patency ratio of 1-year was 96.1% (148/154), and that of 3-year was 88.5% (69/78). The risk factors of the descended patency ratio of stent are respectively the increasing preprocedural white blood cell count, no antiplatelet agents therapy and residual stenosis [OR 3.135 (P < 0.001, 95%CI 1.781 - 5.519); OR 5.818 (P = 0.005, 95%CI 1.688 - 20.057) and OR 5.253 (P = 0.014, 95%CI 1.391 - 19.838)]. There is the significant difference in preprocedural WBC between non-patency group and patency group (t = -5.008, P < 0.001, (8.15 ± 1.59) × 10⁹/L (5.25 × 10⁹/L - 10.75 × 10⁹/L) vs (6.01 ± 1.36) × 10⁹/L (4.07 × 10⁹/L - 8.11 × 10⁹/L). And there are the significant differences in antiplatelet agents therapy and residual stenosis between them (P = 0.002 and P = 0.025). At the end of the survey, the patency ratio of stent in subclavian artery of higher and lower WBC group is respectively 71.1% (32/45) and 98.2% (107/109) (P < 0.01). It's sustainable antiplatelet agents therapy and decreased residual stenosis the stent that key elements to improve the long-term patency ratio of stent planted in subclavian artery. In addition, pay attention to that increasing white blood cell disturbs the long-term patency ratio of stent.