Abstract
Objective To analyze the incidence of urinary stone formation in the contralateral kidney of unilateral nephrectomy patients. Methods 1048 patients, including 596 males and 452 females, underwent unilateral nephrectomy from June 2010 to June 2016. Their age ranged from 16-87 years old (mean 58.7 years old).532 patients combined with components of metabolic syndrome and 213 patients with metabolic syndrome.164 patients had a previous history of urolithiasis.The incidence of urinary stone formation in the contralateral kidney after nephrectomy was recorded and analyzed.The urolithiasis incidences in different gender, age, comorbidity and history of urolithiasis patients after uninephrectomy were compared. Results All patients were followed up within 0.5 to 6 years (mean 3.2 years). 89 patients suffered from urinary stones in the contralateral kidney after uninephrectomy.The incidence of urinary stone formation in the contralateral kidney was 8.5%(89/1048), which was higher than that in general population of China. 1%-5%.The urolithiasis incidence was 9.1%(54/596)in male patients and 7.7%(35/452)in female patients after nephrectomy. The incidence of urinary stone formation was 8.6%(3/35)in patients aged under 30 years old, 12.5%(34/272)in patients aged 30-49 years old, 7.3%(37/504)in patients aged 50-69 years old, 6.3%(15/237)in patients aged 70 and over.The incidence of urinary stone formation was 12.2%(65/532)in patients with components of metabolic syndrome after nephrectomy and 19.7%(42/213)in patients with metabolic syndrome, while the incidence was 4.7%(24/516)in patients without components of metabolic syndrome.In patients with history of urolithiasis, the incidence was up to 30.5%(50/164)after nephrectomy, while 4.4%(39/884)in patients without history of urolithiasis. Conclusions The incidence of urinary stone formation in the contralateral kidney of uninephrectomy patients was higher, especially in patients with metabolic syndrome or urolithiasis history.Patients after unilateral nephrectomy are more vulnerable to urolithiasis. Key words: Uninephrectomy; Urolithiasis; Incidence; Metabolic syndrome
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