Abstract
Objective: To explore the treatment measure of rhabdomyolysis caused by snake bites, and provide guidance for further prevention and control of snake bites. Methods: To retrospectively analyze the 841 cases of serpentine bites in our hospital from January 2006 to July 2017; 127 cases of patients with rhabdomyolysis syndrome were screened out, and their clinical manifestations, laboratory results, related treatment and prognosis were analyzed. Results: 127 cases patients were rhabdomyolysis out of 841 cases, 28 cases patients developed acute renal failure; treatment measures included local wound treatment, application of tetanus antitoxin, anti-snake venom serum, anti-infection, fluid “hydration” and diuretic, alkaline urine and hybrid renal replacement therapy. 112 cases were cured, improved conditions in 9 cases, 3 cases of death, 3 cases uncured. The improvement rate of is 95.26% after treatment. Conclusion: The rhabdomyolysis had a high incidence in snake bite patients, severe cases often developed acute renal failure. Serum myopsin and related biochemical blood tests could be used to diagnose rhabdomyolysis quickly. Combined treatment methods are the main measure to increase the cured rate and decrease the death rate.
Highlights
At present, snake bites still have a high incidence in summer and autumn
To explore the treatment measure of rhabdomyolysis caused by snake bites, and provide guidance for further prevention and control of snake bites
The rhabdomyolysis had a high incidence in snake bite patients, severe cases often developed acute renal failure
Summary
Snake bites still have a high incidence in summer and autumn. Due to the complex composition of snake venom and its quick speed into the blood circulation, it could cause systemic poisoning symptoms after snake bites, and some patients had rhabdomyolysis syndrome (RM) due to a large number of myoglobin (Mb), creatine phosphokinases (CPK) and lactate dehydrogenase. We retrospectively analyzed 841 cases of snake bites patients in our hospital from January 2006 to July 2017 and screened out 127 cases with rhabdomyolysis syndrome. By analyzing its clinical manifestations, laboratory tests, related treatment and prognosis, we hope to provide guidance for further treatment of snake bites
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