The analysis of the risk factors in Uygur in Xinjiang area of the colorectal adenomatous polyosis progressing into the early colorectal cancer

Abstract

Objective To investigate the risk of the colorectal adenomatous polyosis progressing into the early colorectal cancer. Methods 909 cases of colorectal adenomatous polyosis and early colorectal cancer confirmed by pathology were selected form January 2015 to December 2016, to explore the risk of the colorectal adenomatous polyosis progressing into the early colorectal cancer. Results There was marked diefference in age, secondary and tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history between the colorectal adenomatous polyosis and the early colorectal cancer (t=3.139, Χ2=4.439, 10.497, 4.479, 7.842, P 0.05), but there was statistically differences in the frequency of grains intake and the patients of the early colorectal cancer eatting the pickled food (2~3 times Per day) were more than the patients of colorectal adenomatous polyosis (Χ2=13.639, P<0.05). In the Logistic regression analysis, the age, tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history maight be the risk of the colorectal adenomatous polyosis becoming into the early colorectal cancer (OR=2.420, 5.632, 7.623, 5.234, P<0.05). Conclusion The age, tertiary relatives within the family history of colon cancer, smoking history, gallbladder excision history maight be the risk of the colorectal adenomatous polyosis becoming into the early colorectal cancer. Key words: Colorectal neoplasms; Adenoma; Uyger people; Risk factor