Abstract

Introduction. Foreword. Part I: Introduction to the Dementias. Dementia and Alzheimer disease: ancient Greek medicine to modern molecular biology. Epidemiology and impact of dementia. Part II: Evaluation and Diagnosis of Dementia. Neuropsychiatric assessment and diagnosis. Medical evaluation and diagnosis. Neuropsychological assessment in dementia. Neuroimaging. Cognitive disorders as psychobiological processes. Part III: Alzheimer Disease and Other Dementias. Alzheimer disease. Mild cognitive impairment. Vascular cognitive disorder. Dementia with Lewy bodies and other synucleinopathies. Frontotemporal dementia. Traumatic brain injury. Other causes of dementia. Psychiatric disorders in people with dementia. Part IV: Treatment of Dementia. Pharmacologic treatment of neuropsychiatric symptoms. Behavioral and environmental management. Pharmacologic treatment of Alzheimer disease and mild cognitive impairment. Management of advanced dementia. Part V: Caregiving, Legal, and Ethical Issues. Supporting family caregivers. Legal issues. Ethical issues and patterns of practice. Part VI: Dementias: The Future. Biomarkers for the dementias. The molecular and genetic basis of Alzheimer disease. The future of dementia treatment. Prevention of dementia and cognitive decline. Appendixes. History form. Level of function scale. Mental status examination. Neurological examination. Alzheimer's disease cooperative study activities of daily living inventory. Neuropsychiatric inventory: community dwelling version. Agitated behavior in dementia scale. Quality of life in Alzheimer's disease scale. Quality of life in late-stage dementia (QUALID) scale. Resources. Index.

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