Abstract
This study was therefore, designed to investigate the ameliorating effect of uncooked beans on pain sensation using three groups of Swiss white mice (control and test) weighing 20g-30g (n=10 each).The control group received normal rodent chow, while the test group received 15g of uncooked beans in 15g of rodent chow per day and serotonin precursor (5HTP) (0.2mg/15g w/w) diet. Water was given adlibitum while daily food and water intake, as well as body weight changes, were monitored during the 30-day study. The formalin tests were used to assess pain sensation. The results showed that in the formalin test, the frequencies and durations of paw licks and paw attention in both phases of the test was significantly lower (P< 0.05) compared to the control group. Therefore, consumption of uncooked Nigeran beans diet decreases pain sensation in mice.  Â
Highlights
Legumes, called pulses, are another name for beans, peas, and lentils in the United Kingdom
Experimental design The formalin test was used to test for pain sensation as developed by Abbott et al, 1981 [1]
The duration of hind paw lick was significantly lower in the uncooked bean and serotonin precursor fed mice compared to the control group (p
Summary
Called pulses, are another name for beans, peas, and lentils in the United Kingdom Beans, such as the iron beans in Nigeria, are considered as good source of protein, iron, zinc, calcium, dietary fibers, and some minerals and vitamins that may prevent cancer and heart disease [2,7]. In addition to these nutritional components, Nigerian beans are rich in a variety of several phytochemicals with potential health benefits such as flavonoids, alkaloids, saponins, glycosides, and tannin, among others [3,6]. Since beans contain chemicals that can potentially affect neurobehavioral patterns, it is, pertinent to find out whether the chronic consumption of uncooked Nigerian beans diet can ameliorate pain sensation
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
