Abstract
An Allyl-bonded stationary phase, produced by a chlorination—Grignard reaction scheme, is used as an intermediate in the synthesis of a cation-exchange material. The double bond of the allyl phase serves as a site for a free radical addition of bisulfite in the presence of azobisisobutynitrile as a catalyst. The conversion is carried out by both a bulk reaction and an in situ procedure. Both methods result in about 90% conversion to the sulfonated material. The stationary phases are characterized by reaction indices of alkyl aryl ketones and by Fourier transform infrared spectra. Both types of converted colomn materials give satisfactory results for typical separations of amino acids and catecholamines. It appears that the allyl phase can serve as a useful intermediate in the synthesis of new bonded phases.
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