Abstract
Nitrogen (N) is an essential macronutrient for plants and profoundly affects crop yields and qualities. Ammonium (NH4 + ) and nitrate (NO3 - ) are major inorganic N forms absorbed by plants from the surrounding environments. Intriguingly, NH4 + is usually toxic to plants when it serves as the sole or dominant N source. It is thus important for plants to coordinate the utilization of NH4 + and the alleviation of NH4 + toxicity. To fully decipher the molecular mechanisms underlying how plants minimize NH4 + toxicity may broadly benefit agricultural practice. In the current minireview, we attempt to discuss recent discoveries in the strategies for mitigating NH4 + toxicity in plants, which may provide potential solutions for improving the nitrogen use efficiency (NUE) and stress adaptions in crops.
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