Abstract

THE INITIAL plan for studying the menopausal ovary called for an extensive review of 500 case histories from patients 45 years of age and older, with a clinico-pathologic study of their ovaries. Such a study was more than half completed before the routine teaching and hospital duties, complicated by war-time lack of personnel, made it impossible to finish the work in time for this publication. The brief remarks to follow are therefore based on the day-to-day observations of a pathologist who sees the aging ovary as a part of a considerable volume of routine pathological material from a clinic devoted to elective gynecologic surgery. It appears that the human female is endowed at birth with a certain ovarian “capital,” namely, the primordial ova. In this author's experience, there are no new additions to such “capital” by way of oogenesis, either from the germinal epithelium or any other structures in the ovary.

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