Abstract
肝纤维化是多种慢性肝病的共同病理基础,表现为肝脏细胞外基质合成增多,降解减少.近年来肝纤维化的研究有两大进展:一是纤维化发生机制的研究,特别是干细胞和上皮-间质细胞转分化扩展了肝星状细胞(HSC)的可能来源[1];二是肝纤维化无创评价指标的建立,随着肝脏弹性硬度检测等手段的完善,对临床抗肝纤维化的药物治疗也有了更好的手段进行监测和评价[2]。
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