Abstract
Unique chemical, physical, and biological features of carbon nanotubes make them an ideal candidate for myriad applications in industry and biomedicine. Carbon nanotubes have excellent electrical and thermal conductivity, high biocompatibility, flexibility, resistance to corrosion, nano-size, and a high surface area, which can be tailored and functionalized on demand. This review discusses the progress and main fields of bio-medical applications of carbon nanotubes based on recently-published reports. It encompasses the synthesis of carbon nanotubes and their application for bio-sensing, cancer treatment, hyperthermia induction, antibacterial therapy, and tissue engineering. Other areas of carbon nanotube applications were out of the scope of this review. Special attention has been paid to the problem of the toxicity of carbon nanotubes.
Highlights
Carbon nanotubes (CNTs) belong to a new class of nanomaterials that possess unique chemical, physical, and biological properties
Karimi-Maleh et al reported on successful fabrication of biosensor equipped with immobilized DNA on a pencil graphite electrode modified with polypyrrole/functionalized multi-walled carbon nanotubes [51]
Different types of anti-cancer compounds have been proposed and tested in regards their conjunction and functionality with the CNTs [66,67]. As it can be expected, the major efforts have been done towards the conjugation of standard chemotherapeutics with CNTs that have been widely used for cancer treatment in the clinics such as doxorubicin, flutamide, cisplatin, methotrexate, paclitaxel, etc
Summary
Carbon nanotubes (CNTs) belong to a new class of nanomaterials that possess unique chemical, physical, and biological properties. There was a boom in scientific interest involving the utilization of CNTS for bio-medicine, bio-sensing, diagnostics, and therapy This was facilitated by the excellent ability of CNTs to act as carriers of molecules of different origin, including proteins, DNA/RNA, enzymes, and drugs [8]. In addition to their proven delivery capacities, it was demonstrated that CNTs are capable of effectively by-passing the blood–tissue barrier and penetrating cells [9]. This review discusses the progress and main fields of bio-medical use of CNTs based on recently published reports It encompasses synthesis of CNTs and their application for bio-sensing, cancer treatment, hyperthermia induction, antibacterial therapy, and tissue engineering.
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