Abstract

SUMMARYIn Addison's disease the daily output of 17‐ketogenic steroids in isolated 24 hour urine specimens fall below or within the normal range, but is not increased by corticotrophin.In panhypopituitarism the daily output of 17‐ketogenic steroids in isolated 24 hour urine specimens is lowered and may either increase after the exhibition of corticotrophin, but less than normally, or remain unaltered.The daily urinary outputs of 17‐hydroxycorticosteroids and steroidal dihydroxyacetones follow patterns in both conditions.The diagnostic significance of the results is illustrated and some clinical features are noted.

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