The adjuvant effect of a mouthwash containing green tea and hyaluronic acid on the peri-implant parameters: a pilot short-term clinical evaluation

Abstract

The aim of this pilot study was to evaluate the adjuvant effect of a mouthwash containing green tea and hyaluronic acid on the peri-implant clinical parameters in full arch implant-supported fixed prosthesis users. Eleven patients with a total of 75 implants that supported 6 lower total fixed prostheses and 7 upper total fixed prostheses agreed to participate in this short-term pilot study. Patients were submitted to clinical analysis of the implants at baseline and 10 days after initial product use. The probing depth, level of the peri-implant mucosa, clinical attachment level, peri-implant mucosa inflammation index and visible plaque index in each of the 6 sites were evaluated. To perform these analyses all, the prostheses were unscrewed during both intervention points. In general, the newly-developed mouthwash was shown to be safe to use with no signs of negative side effects. Additionally, biofilm and inflammation index were both reduced, with changes in the peri-implant mucosa marginal level due to inflammation reduction. It can be concluded that the mouthwash containing green tea and hyaluronic acid successfully reduced biofilm accumulation and inflammation around dental implants in full arch implant-supported fixed prosthesis safely in a short-term evaluation period.