Abstract
Background and Aims : Saturated fatty acids (SFA) may contribute to the development of atherosclerosis via activation of inflammatory responses and endothelial expression of cell adhesion molecules. Although coconut oil is gaining popularity in the UK diet, little is known about the effects of this plant-derived SFA-rich oil on markers of inflammation and endothelial function. The aim of this study was to compare the effects of SFA-rich oils (coconut oil with butter) and vegetable oils on postprandial plasma cell adhesion molecules (intercellular adhesion molecule-1, vascular adhesion molecule-1(VCAM-1), E-selectin and P-selectin) and cytokine production (interleukin (IL)6, IL-10, IL-1b, tumour necrosis factor a, C-X-C motif chemokine ligand 5 (CXCL5) and C-C motif chemokine ligand 5) in men.
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