Abstract
The authors have studied the activity of alkaline and acid phosphatase in the rat and the mouse vaginal anlage. The activity is high in the epithelium of the mullerian vagina and low or uncertain in that of the sinus vagina. When a lumen is formed in the latter, there appears in rat an activity of both phosphatases of the same intensity as seen in the mullerian vagina. In mouse, the epithelium of the mullerian vagina transitory loses its activity of alkaline phosphatase when the epithelium undergoes transformation. The whole vagina is then surrounded by a zone of high stromal activity of alkaline phosphatase. The epithelium lacks activity except in the fornix region where the activity remains in a zone close to the lumen Thereafter the activity disappears in the subepithelial strorna and instead apears in the basal layer of the epithelium. The activity of acid phosphatase increases in the mouse sinus vagina at the same time as lumen is formed, being of the same intensity here as in the mullerian vaginal part.
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