Abstract
This study was purposed to inquire the activities of benzopyran (chromones) and benzofuranones (coumaranones) derivatives against Steinernema feltiae (S. feltiae). The toxicity assay against S. feltiae showed that benzopyran derivatives 2, 3, 4, 6, and 9 have the highest activityon S. feltiae with viabilities percentage of <50%. The compound 9 demostrated the highest activity with LD50 and LD values, 7.2 and 52.2 μM,respectively. The activities of compound 7 and 10 showed the lowest toxicity. Interestingly, the activity of benzofuranone derivatives showedsignificant activities against S. feltiae. Compare to benzopyran derivatives, the benzofuranone derivatives has the highest toxicity, in particularcompound 13 with LD5.45 μM. The nematicidal assay showed that benzofuranones (coumaranones) derivatives revealed higher activities thanbenzopyran (chromones) derivatives.Key words: chromones, benzopyran, coumaranones, benzofuranone, and Steinernema feltiae 50 90
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More From: Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences
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