Abstract
To study the activating blood and hypolipidemic effects of black mulberry on aged rats, the aged rats were divided into 3 groups and fed with black mulberry fruit or juice respectively. The blood of rats in treatment groups and control group was collected and determined after 8 weeks treatment. The results showed that antioxidant enzymes SOD and GSH-Px were increased in both treatment groups. Na+-K+-ATPase activity, the primary membrane enzyme of rat erythrocytes, was increased when the aged rats were fed black mulberry fruit or juice. The high-density lipoprotein cholesterol (HDL-c) and the erythrocyte membrane fluidity in the blood of rats treated with juice and fruit were improved. Furthermore, mulberry treatment significantly decreased MDA content in the serum and erythrocytes total cholesterol (TC) of rats. The Anti-atherogenic indexes (AAI) were distinguishedly increased in both treatment groups(P<0.05). The results suggested that both the fruit and juice of black mulberry have beneficial effects including activating blood, hypolipidemic and anti-atherosolerosis.
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