Abstract
From our results it is concluded that piperidine can mimic the acetylcholine action on H-cells. The response of the cell membrane to piperidine administration is actuated either by piperidine, or by both piperidine and acetylcholine which was presynaptically released. The piperidine action on D-cells probably directly desensitizes the cholinoceptive sites without changing membrane potential or membrane resistance. Since it has been reported that piperidine physiologically occurs preferentially in the brain of the snail in concentrations comparable to those of other neurotransmitters 6, piperidine might participate in signal processing mechanisms in the nervous system of this species by any of the actions reported here, if it were released in sufficient quantities.
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