Abstract
The second of two monozygous twin boys had perinatal anoxia and spastic diplegia, and developed hypertrophic pyloric stenosis at eight weeks. The coincidence of these conditions, together with the absence of both conditions in the twin, suggests that anoxia may be important in precipitating pyloric stenosis in hereditarily disposed infants. Previous work showing an increased incidence of pyloric stenosis in first born children may indicate a similar precipitating factor.
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