Abstract
Abstract 1.1. Experiments have been presented showing that avertin manifests a definite action on both voluntary and nonvoluntary muscle. 2.2. Applied directly to voluntary muscle, it decreases the irritability and produces a rigor-like phenomenon. 3.3. After absorption into the blood stream, it does not affect skeletal muscle substance directly, but effects relaxation through nervous depression. 4.4. Avertin depresses all kinds of nonvoluntary muscle, both on direct application and after absorption into the blood stream. 5.5. The depressant effects in the intact animal are exhibited more uniformly and more acutely on the bladder, rectum, and uterus. 6.6. Avertin does not qualitatively alter the reactions of tissue to nerve and muscle stimulants and depressants.
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