Abstract

The purpose of this study was to determine the effect of adrenalin on the heart rate and rhythm of patients with auriculoventricular dissociation subject to Stokes-Adams seizures. It is now definitely established that recurrent syncopal attacks in such patients may be the result of either ventricular slowing and standstill 1 or of the various grades of acceleration of the ventricles leading to transient ventricular fibrillation. 2 While there are now some excellently controlled observations on the action of adrenalin in patients with auriculoventricular dissociation and standstill of the ventricles, both preceding and during the presence of syncope, there are no comparable analyses of the cardiac mechanism following the use of the drug in patients subject to transient periods of ventricular fibrillation. This is of particular importance at the present time, since adrenalin is being prescribed indiscriminately in patients with Stokes-Adams seizures without any knowledge of the mechanism responsible for the attacks.

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