Abstract
THE DIVISION of chromosome material is associated with the activity of the spindle apparatus which does not stain like chromatin and is often called the achromatic figure. Its structure in many plant and animal cells both in vivo and after a variety of technical procedures has been studied by many workers. Their observations have disagreed in many ways. A number of interpretations of the achromatic figure's mode of function have arisen. Many earlier accounts of mitosis have been reviewed by Hughes (1952), Schrader (1953), and Ris (1955). Schrader lists a number of theories dealing with the mode of action of the spindle apparatus; none of these, his evaluation makes clear, satisfies all established facts. Clearly the nature of the forces which bring about mitosis, promote the formation of the spindle and carry the mitosis to its conclusion is puzzling.
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