Abstract
To the Editor: Mohs micrographic surgery (MMS) for melanoma is controversial because of concerns about the accuracy of detecting melanoma on frozen sections. This study's primary analysis examined the sensitivity and specificity of detecting melanoma using hematoxylin and eosin (H&E) and melanoma-associated antigen recognized by T cells (MART-1) frozen sections compared with permanent sections. The secondary analysis evaluated whether frozen section specimens can be subsequently processed for permanent sections without diminishing diagnostic accuracy.
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