Abstract
Purpose of the study. To improve of innate immune disorders diagnosis in preschool children with respiratory tract recurrent infectious diseases on the basis of new data of phagocytosis parameters by studying its absorption and prooxidant characteristics.
 Materials and methods. Under observation were 60 children aged 2 to 5 years. Two groups were formed: 1). children with respiratory tract acute infectious more than 6 times in year (n = 30); 2). children with respiratory tract acute infectious 6 or less times in year (n = 30).
 Results. Among children in 1 group, statistically significantly increased the registration quantity of low phagocytic counts (by 60,0%, p < 0,05), phagocytic index (by 56,0%, p < 0,05), index of phagocytosis completeness (70,0%, p < 0,05), neutrophil phagocytic activity stimulated by staphylococcus (50,0%, p < 0,05) and high rates of spontaneous neutrophil phagocytic activity (43,3%, p < 0,05), high serum levels of lipid hydroperoxides (by 80,0%, p < 0,05), diene conjugates (by 80,0%, p < 0,05), malonic dialdehyde (76,7%, p < 0.05), diene ketones (76,7%, p < 0,05), Schiff bases (76,7%, p < 0,05).
 Conclusion. In children 2–5 years with respiratory tract acute infectious more than 6 times in year the phagocytic dysfunction and increased lipid peroxidation were established. It is characterizing the failure and slowness of the early immune response.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.