Abstract
IN 1929 we published evidence (Proc. Roy. Soc., B, 104, 561; 1929) showing that in preparations made from ergosterol by exposure to ultra-violet radiation, and subsequent removal of unchanged ergosterol, there was a close correlation between antirachitic activity and intensity of absorption for radiation of wave-length 280 mμ. On this and on other evidence we argued that it was probable that vitamin D was the substance present in these products which was responsible for the intense absorption band with heads at 280 mμ, and 271 m (substance A). We have now obtained definite evidence that this inference is not correct, and that the reactions which occur on irradiation of ergosterol are more complex than then appeared probable.
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