Abstract
The ability of whole-body suvmax in f-FDG PET/CT to predict suboptimal cytoreduction during primary debulking surgery for advanced ovarian cancer
Highlights
The aim of this study was to (1) evaluate the ability of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) parameters to predict suboptimal cytoreduction and (2) to create a risk model for predicting suboptimal cytoreduction in advanced ovarian cancer
More than 70% of patients with ovarian cancer are diagnosed at an advanced stage (International Federation of Gynecology and Obstetrics [FIGO] stage III or IV), and the 5-year survival rate is less than 30% [2]
Optimal cytoreduction was achieved in 34 patients (66.7%); ; 17 patients (33.3%) had > 1-cm residual disease
Summary
The aim of this study was to (1) evaluate the ability of F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) parameters to predict suboptimal cytoreduction and (2) to create a risk model for predicting suboptimal cytoreduction in advanced ovarian cancer. From 2011 to 2015, 51 patients underwent primary cytoreductive surgery for advanced ovarian cancer were enrolled. F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) may be helpful in validating the selection and management of recurrent ovarian cancer patients by identification of extra-abdominal disease and may allow adequate planning of surgical debulking at retroperitoneal, hepatic, or splenic sites [11, 12]. The role of FDG PET/CT in predicting the outcome of primary optimal cytoreductive surgery for advanced ovarian cancer has not been reported
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