Abstract
We stand poised on the threshold of a new era in care for acute ischemic stroke, in which treatments will be swift, starting in the first 60 minutes after onset, the “golden hour” when almost the entire threatened brain region is still salvageable, and treatments will be sure, reopening occluded arteries in almost all patients who will benefit from reperfusion. This narrative review surveys translational clinical research in prehospital neuroprotection and highly effective endovascular recanalization therapy that has helped lay the foundation for this imminent transformation.
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