Abstract
Masao Matsuoka wins the 2011 Retrovirology Prize.
Highlights
Seven years ago, Retrovirology inaugurated an annual prize to recognize the achievements of a deserving retrovirologist [1]
LTR DNA sequence of the human T-cell leukemia virus type 1 (HTLV-1) provirus is preferentially methylated while the 3’ LTR of the provirus is not
His work in this area is independent of and contemporaneous with similar observations made in human immunodeficiency virus type 1 (HIV-1) research and has added to our insights on how retroviral latency is achieved and how it might be thwarted by employing targeted therapeutic agents
Summary
Retrovirology inaugurated an annual prize to recognize the achievements of a deserving retrovirologist [1]. For the past 25 years, Matsuoka has been a pioneer and a leading figure in human T-cell leukemia virus type 1 (HTLV-1) research. HIV-1 researchers have long ago discounted the importance of a 3’ LTR driven antisense transcript. In the last decade, independent results from Mesnard (France) and Matsuoka (Japan) have strongly established the existence and biological importance of an HTLV-1 antisense transcript called HBZ.
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