Abstract
Conclusions: Apixaban is less effective in reducing thrombus burden than enoxaparin at 2and 14-day time points in this nonstasis murine model of DVT. This may be due to anti-inflammatory pleiotropic effects of enoxaparin that apixaban may not have in acute DVT. Further study is ongoing to determine whether vein wall remodeling is affected by Xa inhibition and whether this is an effect of apixaban itself or a class effect of anti-Xa inhibitors.
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Schedule a callMore From: Journal of Vascular Surgery: Venous and Lymphatic Disorders
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