Abstract
This autumn, approximately 100 scientists and students from the Rocky Mountain area along with invited speakers attended the 18th annual meeting of the Rocky Mountain Virology Association that was held at the Colorado State University Mountain Campus. The two-day gathering featured 31 talks and 33 posters all of which focused on specific areas of current virology and prion protein research. Since the keynote presentation focused on the oligoadenylate synthetase-ribonuclease L pathway the main area of focus was on host–virus interactions, however other areas of interest included virus vectors, current models of virus infections, prevention and treatment of virus infections, separate sessions on RNA viruses and prion proteins, and a special talk highlighting various attributes of targeted next-generation sequencing. The meeting was held at the peak of the fall Aspen colors surrounded by five mountains >11000 ft (3.3 km) where the secluded campus provided the ideal setting for extended discussions and outdoor exercise. On behalf of the Rocky Mountain Virology Association, this report summarizes 42 selected presentations.
Highlights
The Rocky Mountain Virology Association was conceived in 2000 to be a regional gathering of virologists where current scientific data is discussed and new ideas shared
Endogenous cellular dsRNA, which accumulates in the absence of ADAR1, can cellular dsRNA, which accumulates in the absence of ADAR1, can activate ribonuclease L (RNase L) and lead to activate RNase L and lead to apoptotic cell death
With several types of viruses, especially coronaviruses. They found that activation in human. They found that RNase L activation in human cells was dependent on OAS3, but independent of cells was dependent on
Summary
The Rocky Mountain Virology Association was conceived in 2000 to be a regional gathering of virologists where current scientific data is discussed and new ideas shared. The venue was selected to be sufficiently removed from urban setting to enhance attendance at all presentations and free time was provided to explore the beautiful mountain setting. The meeting has grown to include significant contributions from prion biologists. With many national and international speakers, the meeting has grown past its regional focus, but has still retained its unique ability to provide a forum to advance science and mentorship. The 18th annual Rocky Mountain Virology Association meeting (Figure 1) continued its legacy of virology, prion biology, and mentorship at an altitude of 9000 ft (2.7 km).
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