Abstract

The achievements in Ebola virus disease (EVD) prevention and control can be reflected by scientific studies, particularly in the top-cited studies. The study thus aimed to identify and characterise the 100 top-cited studies of EVD. The study used a retrospective bibliometric-analysis, which was performed in January 2020. Studies were searched from the Web of Science using keywords: “Ebola” or “Ebola virus” or “Ebola virus disease” to identify the 100 top-cited EVD studies. Studies were analysed for the number of citations, authorship, and journal, year of publication, country and institution. The analyses were carried out using SPSS, HistCite and VOSviewer. The 100 top-cited studies were published between 1977 and 2017, cited from 169 to 808 times and had an average citation of 290.5, and 8 studies were cited more than 500 times. They were published in 31 journals, and the Journal of Virology published most of the studies (n=14). They were produced by 33 countries, and the USA published most of the studies (63), followed by Germany (8) and Gabon (6). CDC-USA (26) was the leading institution, while Geisbert TW and Sanchez A were the most productive authors. This study provides insights into the historical advancements reflected by the top-cited studies and has highlighted the leading roles played by various stakeholders in addressing EVD. However, the contribution of African countries is not sufficiently reflected among these studies, and so more focus, funding and involvement in clinical research is needed for effective prevention and control of EVD in Africa.

Highlights

  • Ebola virus disease (EVD) is a severe, often fatal zoonosis that is highly infectious in humans [1]

  • Evaluation of the 100 top-cited studies had been conducted for various medical fields and diseases, including Gastritis [15], Depression [14], Vaccines [16], Arthritis [17], among others

  • The study has characterised, and provided insights into the historical advancements of EVD research reflected through the top-cited studies

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Summary

INTRODUCTION

Ebola virus disease (EVD) is a severe, often fatal zoonosis that is highly infectious in humans [1]. It is caused by negativestranded RNA viruses, belonging to the Filoviridae family, which are endemic to regions of the west and equatorial Africa [2]. Despite the recurrent outbreaks and other challenges, several studies on Ebola have been conducted over time, with remarkable progress in vaccine development [7], as well as prevention and control of EVD [8,9]. Evaluation of the 100 top-cited studies had been conducted for various medical fields and diseases, including Gastritis [15], Depression [14], Vaccines [16], Arthritis [17], among others. We performed this study to identify and characterise the 100 topcited studies of Ebola virus disease

METHODS
Search Method and Strategy
CONCLUSIONS
A Case of Severe Ebola Virus Infection Complicated by Gram-Negative Septicemia
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