Abstract

Aim: The basic aim of this analysis was to evaluate the 100 most cited publications in aging research. Methods: On January 17, 2021 Web of Science Core Collection database was searched for aging research publications. The studied parameter includes; publication year, authorship, publication type, keywords, journal name, institution, country, and visualization mapping. HistCiteTM application for citation analysis and VOSviewer software was used for visualization mapping. Results: The top 100 most cited papers were published in 52 journals, authored by 537 authors. The most cited paper was “The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease,” which received 6039 citations (2013 average citations per year). Nature was the most attractive journal (n=13). Aging was the most dominant used keyword. The maximum number of papers were published in 2005 (n=8). Harvard University was the leading institute (n=13), while the United States of America (USA) was the most productive country (n=76). Conclusion: The highly cited papers were published in developed countries, and no study was published in low-income countries.

Highlights

  • Biological aging involves a broad range of life changes that negatively impact all fundamental biological processes and lead to loss of organismal homeostasis and eventually death [1,2]

  • The top 100 most cited papers were published in 52 journals with 6716 cited references, 407 keywords, and 537 authors

  • Based on TLS, aging and dementia were the most widely used author keywords (TLS=49), and (TLS=16) respectively as shown in Bibliometric type studies are of great interest, providing an overview of the scientific published literature and other important parameters [22]

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Summary

Introduction

Biological aging (evry living organism) involves a broad range of life changes that negatively impact all fundamental biological processes and lead to loss of organismal homeostasis and eventually death [1,2]. Human aging (related to human lives) annexes the macroscopic changes, including grinding of the skin, wrinkling, loss of muscle, and physical weakness. They are more vulnerable to a wide range of diseases when individuals get older. Age-dependent molecular damage accumulates lower DNA or protein stability, energy production, utilization failure, and homeostasis disruption leading to structural and functional decline

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