THALLIUM-201 SPECT PERFORMED IN CONJUNCTION WITH TC 99M PYP IMPROVES QUANTIFICATION AND DIAGNOSTIC ACCURACY OFTC 99M PYP UPTAKE FOR ASSESSMENT OF PATIENTS WITH SUSPECTED CARDIAC AMYLOIDOSIS

Abstract

Myocardial Tc-99m-pyrophosphate (Tc-99m PYP) uptake is used to distinguish transthyretin associated amyloid (ATTR) from primary light chain amyloid (AL). With Tc-99m PYP SPECT alone, differentiation of myocardium and the blood pool may be imprecise and quantification of Tc-99m PYP uptake may be