Abstract

1. 1) A simple rapid test designed to detect an increased erythrocyte osmotic resistance has been used to assess the frequency of thalassaemia minor in 1,416 school children of Egyptian, and 362 of mixed Egyptian-Sudanese Arab parentage. A solution of sodium chloride (0.35 per cent.) was used as the haemolysing solution. Reasons are given why this concentration of sodium chloride was chosen as the critical hypotonic solution. 2. 2) The frequency of thalassaemia minor in Egyptian children was 23.37 per cent.; that in the children of mixed parentage was 27.90 per cent. 3. 3) It is suggested that thalassaemia major is more frequent in Egypt than is indicated by the number of reports from that country in the literature.

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